Performance Tweaks
From The DarkMod Wiki
				Valid for all Releases
- Run Doom3 in fullscreen
 - Turn the video resolution down
 - Turn down anisotropic filtering (in DoomConfig.cfg), because it defaults to 8
 - Turn off "High SFX" in the graphic settings
 
Releases after Thief's Den
- set the "Ambient Rendering" to "Fast"