Motion Builder - Mirroring an existing animation
From The DarkMod Wiki
If you're not already in Animation layout, press Ctrl+Shift+2
In the Character Controls pane, click Edit, Plot Character, Skeleton
Press Ctrl+Shift+1 to go to Creation layout
In the Navigation pane, expand "Characters" and double click the name of your character
Under the Character Settings tab, click the Mirror check box
Press Ctrl+Shift+2 to return to Animation Layout
Once again, in the Character Controls pane, click Edit, Plot Character, Skeleton
The character will be facing the opposite way now though (to the back), so use the rotation options in the export section of the .def file to flip it 180 the right way around.